Giles Hardingham: search on Z-Library

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1

Mixed-species RNA-seq for elucidation of non-cell-autonomous control of gene transcription

Qiu, Jing, Dando, Owen, Baxter, Paul S., Hasel, Philip, Heron, Samuel, Simpson, T. Ian, Hardingham, Giles E.

Journal:

Nature Protocols

Year:

2018

Language:

english

File:

PDF, 990 KB

english, 2018

2

Calcium as a versatile second messenger in the control of gene expression

Hardingham, Giles E., Bading, Hilmar

Journal:

Microscopy Research and Technique

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

3

Antiphase disorder in GaAs/Ge heterostructures for solar cells

L. Lazzarini, L. Nasi, G. Salviati, C.Z. Fregonara, Y. Li, L.J. Giling, C. Hardingham, D.B. Holt

Journal:

Year:

2000

Language:

english

File:

PDF, 871 KB

english, 2000

4

Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated

Giles E Hardingham, Hilmar Bading

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2002

Language:

english

File:

PDF, 191 KB

english, 2002

5

Synaptic activity induces signalling to CREB without increasing global levels of cAMP in hippocampal neurons

Anna Pokorska, Peter Vanhoutte, Fiona J. L. Arnold, Francesca Silvagno, Giles E. Hardingham, Hilmar Bading

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 182 KB

english, 2003

6

Cellular Notch responsiveness is defined by phosphoinositide 3-kinase-dependent signals

Grahame Mckenzie, George Ward, Yvette Stallwood, Emmanuel Briend, Sofia Papadia, Andrew Lennard, Martin Turner, Brian Champion, Giles E Hardingham

Journal:

BMC Cell Biology

Year:

2006

Language:

english

File:

PDF, 1015 KB

english, 2006

7

Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin

Francesc X. Soriano, Paul Baxter, Lyndsay M. Murray, Michael B. Sporn, Thomas H. Gillingwater, Giles E. Hardingham

Journal:

Molecules and Cells

Year:

2009

Language:

english

File:

PDF, 203 KB

english, 2009

8

Human Embryonic Stem Cell-Derived Neurons as a Tool for Studying Neuroprotection and Neurodegeneration

Giles E. Hardingham, Rickie Patani, Paul Baxter, David J. Wyllie, Siddharthan Chandran

Journal:

Molecular Neurobiology

Year:

2010

Language:

english

File:

PDF, 180 KB

english, 2010

9

To Die or Not To Die? Current Questions in Cell Death Signalling

H. Anne Leaver, Giles Hardingham

Journal:

Molecular Neurobiology

Year:

2010

Language:

english

File:

PDF, 75 KB

english, 2010

10

Nuclear Ca2+ and CaM kinase IV specify hormonal- and Notch-responsiveness

Grahame J. Mckenzie, Patrick Stevenson, George Ward, Sofia Papadia, Hilmar Bading, Sangeeta Chawla, Martin Privalsky, Giles E. Hardingham

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 876 KB

english, 2005

11

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione

Francesc X. Soriano, Frédéric Léveillé, Sofia Papadia, Larry G. Higgins, James Varley, Paul Baxter, John D. Hayes, Giles E. Hardingham

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 645 KB

english, 2008

12

Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons

Michael Fricker, Sofia Papadia, Giles E. Hardingham, Aviva M. Tolkovsky

Journal:

Journal of Neurochemistry

Year:

2010

Language:

english

File:

PDF, 677 KB

english, 2010

13

Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1

Paul S. Baxter, Marc-Andre Martel, Aoife McMahon, Peter C. Kind, Giles E. Hardingham

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 491 KB

english, 2011

14

Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

Hardingham, Giles E., Chawla, Sangeeta, Johnson, Claire M., Bading, Hilmar

Journal:

Year:

1997

File:

PDF, 1.61 MB

1997

15

10.1038/85109

Hardingham, Giles E., Arnold, Fiona J. L., Bading, Hilmar

Journal:

Nature Neuroscience

Year:

2001

Language:

english

File:

PDF, 1.74 MB

english, 2001

16

10.1038/88380

Hardingham, Giles E., Arnold, Fiona J. L., Bading, Hilmar

Journal:

Nature Neuroscience

Year:

2001

Language:

english

File:

PDF, 409 KB

english, 2001

17

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

Hardingham, Giles E., Fukunaga, Yuko, Bading, Hilmar

Journal:

Nature Neuroscience

Year:

2002

Language:

english

File:

PDF, 1.34 MB

english, 2002

18

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

Hardingham, Giles E., Bading, Hilmar

Journal:

Nature Reviews Neuroscience

Year:

2010

Language:

english

File:

PDF, 762 KB

english, 2010

19

2B synaptic or extrasynaptic determines signalling from the NMDA receptor

Giles. E. Hardingham

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

20

Compartmentalized NMDA receptor signalling to survival and death

Francesc X. Soriano, Giles E. Hardingham

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 265 KB

english, 2007

21

Nuclear calcium: a key regulator of gene expression

Giles E Hardingham, Hilmar Bading

Journal:

Year:

1998

Language:

english

File:

PDF, 109 KB

english, 1998

22

The influence of synaptic activity on neuronal health

Karen FS Bell, Giles E Hardingham

Journal:

Current Opinion in Neurobiology

Year:

2011

Language:

english

File:

PDF, 276 KB

english, 2011

23

Mechanisms controlling gene expression by nuclear calcium signals

Giles E. Hardingham, Francisco H. Cruzalegui, Sangeeta Chawla, Hilmar Bading

Journal:

Year:

1998

Language:

english

File:

PDF, 918 KB

english, 1998

24

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

Rickie Patani, Patrick A. Lewis, Daniah Trabzuni, Clare A. Puddifoot, David J. A. Wyllie, Robert Walker, Colin Smith, Giles E. Hardingham, Michael Weale, John Hardy, Siddharthan Chandran, Mina Ryten

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 974 KB

english, 2012

25

CNS Peroxiredoxins and Their Regulation in Health and Disease

Bell, Karen F.S., Hardingham, Giles E.

Journal:

Antioxidants & Redox Signaling

Year:

2011

Language:

english

File:

PDF, 483 KB

english, 2011

26

Gene Regulation by Nuclear and Cytoplasmic Calcium Signals

Hilmar Bading, Giles E. Hardingham, Claire M. Johnson, Sangeeta Chawla

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 76 KB

english, 1997

27

The Yin and Yang of NMDA receptor signalling

Giles E. Hardingham, Hilmar Bading

Journal:

Trends in Neurosciences

Year:

2003

Language:

english

File:

PDF, 282 KB

english, 2003

28

Control of Recruitment and Transcription-Activating Function of CBP Determines Gene Regulation by NMDA Receptors and L-Type Calcium Channels

Giles E. Hardingham, Sangeeta Chawla, Francisco H. Cruzalegui, Hilmar Bading

Journal:

Year:

1999

Language:

english

File:

PDF, 358 KB

english, 1999

29

Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response

Alberto Camacho, Sergio Rodriguez-Cuenca, Margaret Blount, Xavier Prieur, Nuria Barbarroja, Maria Fuller, Giles E. Hardingham, Antonio Vidal-Puig

Journal:

Experimental Neurology

Year:

2012

Language:

english

File:

PDF, 1.78 MB

english, 2012

30

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites

Soriano, Francesc X., Chawla, Sangeeta, Skehel, Paul, Hardingham, Giles E.

Journal:

Journal of Neurochemistry

Year:

2013

Language:

english

File:

PDF, 569 KB

english, 2013

31

NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons

Gupta, Kunal, Hardingham, Giles E., Chandran, Siddharthan

Journal:

Neuroscience Letters

Year:

2013

Language:

english

File:

PDF, 452 KB

english, 2013

32

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

Hardingham, Giles E.

Journal:

Biochemical Society Transactions

Year:

2009

Language:

english

File:

PDF, 447 KB

english, 2009

33

Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure

McKay, Sean, Bengtson, C. Peter, Bading, Hilmar, Wyllie, David J.A., Hardingham, Giles E.

Journal:

Neuropharmacology

Year:

2013

Language:

english

File:

PDF, 623 KB

english, 2013

34

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals

Qiu, Jing, Tan, Yan-Wei, Hagenston, Anna M., Martel, Marc-Andre, Kneisel, Niclas, Skehel, Paul A., Wyllie, David J. A., Bading, Hilmar, Hardingham, Giles E.

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 2.04 MB

english, 2013

35

Corrigendum to “Ablation of PGC1 beta prevents mTOR dependent endoplasmic reticulum stress response” [Exp. Neurol. 237/2 (2012) 396–406]

Camacho, Alberto, Rodriguez-Cuenca, Sergio, Blount, Margaret, Prieur, Xavier, Barbarroja, Nuria, Fuller, Maria, Hardingham, Giles E., Vidal-Puig, Antonio

Journal:

Experimental Neurology

Year:

2013

Language:

english

File:

PDF, 106 KB

english, 2013

36

Regulation of Neuronal Oxidative and Nitrosative Stress by Endogenous Protective Pathways and Disease Processes

Hardingham, Giles E., Lipton, Stuart A.

Journal:

Antioxidants & Redox Signaling

Year:

2011

Language:

english

File:

PDF, 100 KB

english, 2011

37

Ionotropic GABA and glycine receptor subunit composition in human pluripotent stem cell-derived excitatory cortical neurones

James, Owain T., Livesey, Matthew R., Qiu, Jing, Dando, Owen, Bilican, Bilada, Haghi, Ghazal, Rajan, Rinku, Burr, Karen, Hardingham, Giles E., Chandran, Siddharthan, Kind, Peter C., Wyllie, David J. A

Journal:

The Journal of Physiology

Year:

2014

Language:

english

File:

PDF, 853 KB

english, 2014

38

Neuronal Activity Controls the Antagonistic Balance Between Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α and Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptors in Regulating Antioxidant Defenses

Soriano, Francesc X., Léveillé, Frédéric, Papadia, Sofia, Bell, Karen F.S., Puddifoot, Clare, Hardingham, Giles E.

Journal:

Antioxidants & Redox Signaling

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

39

Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration

Gupta, Kunal, Chandran, Siddharthan, Hardingham, Giles E.

Journal:

British Journal of Clinical Pharmacology

Year:

2013

Language:

english

File:

PDF, 953 KB

english, 2013

40

Selective dendritic susceptibility to bioenergetic, excitotoxic and redox perturbations in cortical neurons

Hasel, Philip, Mckay, Sean, Qiu, Jing, Hardingham, Giles E.

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2015

Language:

english

File:

PDF, 2.59 MB

english, 2015

41

Effect of a GRIN2A de novo mutation associated with epilepsy and intellectual disability on NMDA receptor currents and Mg2+ block in cultured primary cortical neurons

Marwick, Katie, Skehel, Paul, Hardingham, Giles, Wyllie, David

Journal:

Year:

2015

Language:

english

File:

PDF, 62 KB

english, 2015

42

Synaptic NMDA receptor activity is coupled to the transcriptional control of the glutathione system

Baxter, Paul S., Bell, Karen F.S., Hasel, Philip, Kaindl, Angela M., Fricker, Michael, Thomson, Derek, Cregan, Sean P., Gillingwater, Thomas H., Hardingham, Giles E.

Journal:

Nature Communications

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

43

Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2

Soriano, Francesc X., Papadia, Sofia, Bell, Karen F. S., Hardingham, Giles E.

Journal:

Year:

2009

Language:

english

File:

PDF, 1.72 MB

english, 2009

44

Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis

Hardingham, Giles E., Do, Kim Q.

Journal:

Nature Reviews Neuroscience

Year:

2016

Language:

english

File:

PDF, 490 KB

english, 2016

45

Synaptic NMDAR activity suppresses FOXO1 expression via a cis-acting FOXO binding site: FOXO1 is a FOXO target gene

Mubarak, Bashayer, Soriano, Francesc X., Hardingham, Giles E.

Journal:

Year:

2009

Language:

english

File:

PDF, 516 KB

english, 2009

46

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression

Martel, Marc-Andre, Soriano, Frances X., Baxter, Paul, Rickman, Colin, Duncan, Rory, Wyllie, David J.A., Hardingham, Giles E.

Journal:

Year:

2009

Language:

english

File:

PDF, 475 KB

english, 2009

47

Hypothermic modulation of human cortical neurons to explore a role for tau protein in neuroprotection

Rzechorzek, Nina M, Connick, Peter, Livesey, Matthew R, Borooah, Shyamanga, Patani, Rickie, Burr, Karen, Story, David, Wyllie, David J A, Hardingham, Giles E, Chandran, Siddharthan

Journal:

Year:

2016

Language:

english

File:

PDF, 54 KB

english, 2016

48

Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition

Rzechorzek, Nina M., Connick, Peter, Livesey, Matthew R., Borooah, Shyamanga, Patani, Rickie, Burr, Karen, Story, David, Wyllie, David J.A., Hardingham, Giles E., Chandran, Siddharthan

Journal:

Year:

2016

Language:

english

File:

PDF, 2.65 MB

english, 2016

49

Adaptive regulation of the brain’s antioxidant defences by neurons and astrocytes

Baxter, Paul S., Hardingham, Giles E.

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 805 KB

english, 2016

50

CONTROL OF RECRUITMENT AND ACTIVATION OF CBP DETERMINES GENE REGULATION BY NMDA RECEPTORS AND L-TYPE CALCIUM CHANNELS

Hardingham, Giles E., Chawla, Sangeeta, Cruzalegui, Francisco H., Bading, Hilmar

Journal:

Biochemical Society Transactions

Year:

1999

Language:

english

File:

PDF, 142 KB

english, 1999